| Pos | Name | Team | Week | Pass | Rush | Rec | TD | Conv | FG | XP | Pts | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | QB | Jay Cutler | MHB | 2/2008 | 350 | 6 | 0 | 4 | 1 | 0 | 0 | 30 |
| 2. | QB | Matt Cassel | BP | 12/2008 | 415 | 14 | 0 | 4 | 0 | 0 | 0 | 29 |
| 3. | QB | Drew Brees | LFT | 12/2008 | 323 | 0 | 0 | 4 | 0 | 0 | 0 | 28 |
| RB | Michael Turner | FM | 12/2008 | 0 | 117 | 0 | 4 | 0 | 0 | 0 | 28 | |
| RB | Brian Westbrook | AE | 13/2008 | 0 | 110 | 20 | 4 | 0 | 0 | 0 | 28 | |
| 6. | RB | DeAngelo Williams | MT | 13/2008 | 0 | 72 | 14 | 4 | 0 | 0 | 0 | 26 |
| 7. | RB | Steven Jackson | FM | 7/2008 | 0 | 160 | 16 | 3 | 0 | 0 | 0 | 24 |
| 8. | QB | Jay Cutler | MHB | 10/2008 | 447 | 29 | 0 | 3 | 0 | 0 | 0 | 23 |
| 9. | QB | Drew Brees | LFT | 4/2008 | 363 | -1 | 0 | 3 | 0 | 0 | 0 | 22 |
| QB | Donovan McNabb | CC | 1/2008 | 361 | 3 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Kurt Warner | MT | 2/2008 | 361 | 0 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Drew Brees | LFT | 1/2008 | 343 | -2 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tony Romo | AE | 12/2008 | 341 | -3 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Drew Brees | LFT | 8/2008 | 339 | -26 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tony Romo | AE | 13/2008 | 331 | 14 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Kurt Warner | MT | 10/2008 | 328 | 0 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tony Romo | AE | 6/2008 | 321 | 0 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Drew Brees | LFT | 6/2008 | 320 | 7 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Aaron Rodgers | SD | 5/2008 | 313 | 4 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tony Romo | AE | 2/2008 | 312 | -5 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Ben Roethlisberger | FM | 5/2008 | 309 | 2 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tony Romo | AE | 4/2008 | 300 | 7 | 0 | 3 | 0 | 0 | 0 | 22 | |
| RB | LenDale White | AO | 7/2008 | 0 | 149 | 7 | 3 | 0 | 0 | 0 | 22 | |
| RB | Thomas Jones | BB | 10/2008 | 0 | 149 | 0 | 3 | 0 | 0 | 0 | 22 | |
| RB | Willie Parker | LMM | 1/2008 | 0 | 138 | 0 | 3 | 0 | 0 | 0 | 22 |