| Pos | Name | Team | Week | Pass | Rush | Rec | TD | Conv | FG | XP | Pts | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | QB | Brett Favre | BB | 4/2005 | 303 | 12 | 0 | 4 | 2 | 0 | 0 | 32 |
| 2. | QB | Jake Plummer | AO | 8/2005 | 309 | 22 | 0 | 4 | 0 | 0 | 0 | 28 |
| 3. | QB | Donovan McNabb | CC | 4/2005 | 369 | -1 | 0 | 3 | 1 | 0 | 0 | 24 |
| QB | Carson Palmer | MB | 12/2005 | 302 | 14 | 0 | 3 | 1 | 0 | 0 | 24 | |
| QB | Peyton Manning | UH | 4/2005 | 264 | 3 | 0 | 4 | 0 | 0 | 0 | 24 | |
| 6. | QB | Ben Roethlisberger | FM | 13/2005 | 386 | 2 | 0 | 3 | 0 | 0 | 0 | 22 |
| QB | Peyton Manning | UH | 11/2005 | 365 | -3 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Tom Brady | BP | 5/2005 | 350 | 1 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Brett Favre | BB | 2/2005 | 342 | 19 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Jake Delhomme | LFT | 8/2005 | 341 | 2 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Carson Palmer | MB | 2/2005 | 337 | 3 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Drew Brees | CC | 8/2005 | 324 | 1 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Peyton Manning | UH | 9/2005 | 321 | 24 | 0 | 3 | 0 | 0 | 0 | 22 | |
| QB | Daunte Culpepper | LMM | 3/2005 | 300 | 36 | 0 | 3 | 0 | 0 | 0 | 22 | |
| 15. | QB | Mike Vick | BuB | 10/2005 | 209 | 24 | 0 | 3 | 1 | 0 | 0 | 20 |
| 16. | QB | Eli Manning | BB | 12/2005 | 344 | 15 | 0 | 2 | 1 | 0 | 0 | 18 |
| QB | Peyton Manning | UH | 10/2005 | 297 | 4 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Marc Bulger | MT | 3/2005 | 292 | 3 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Kerry Collins | CR | 1/2005 | 265 | 2 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Tom Brady | BP | 9/2005 | 265 | -1 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Mark Brunell | MHB | 7/2005 | 252 | 0 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Carson Palmer | MB | 8/2005 | 237 | 0 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Carson Palmer | MB | 13/2005 | 227 | -3 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Tom Brady | BP | 11/2005 | 222 | 5 | 0 | 3 | 0 | 0 | 0 | 18 | |
| QB | Eli Manning | BB | 11/2005 | 218 | 7 | 0 | 3 | 0 | 0 | 0 | 18 |