| Pos | Name | Team | Week | Pass | Rush | Rec | TD | Conv | FG | XP | Pts | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. | QB | Drew Brees | CC | 12/2016 | 310 | 1 | 0 | 5 | 0 | 0 | 0 | 34 |
| 2. | QB | Matt Ryan | FM | 4/2016 | 503 | 14 | 0 | 4 | 0 | 0 | 0 | 30 |
| QB | Andrew Luck | MT | 1/2016 | 385 | 21 | 0 | 4 | 1 | 0 | 0 | 30 | |
| 4. | QB | Drew Brees | CC | 6/2016 | 465 | 0 | 0 | 4 | 0 | 0 | 0 | 29 |
| QB | Drew Brees | CC | 1/2016 | 423 | 5 | 0 | 4 | 0 | 0 | 0 | 29 | |
| 6. | QB | Ben Roethlisberger | LMM | 5/2016 | 380 | 0 | 0 | 4 | 0 | 0 | 0 | 28 |
| QB | Philip Rivers | AE | 5/2016 | 359 | 0 | 0 | 4 | 0 | 0 | 0 | 28 | |
| QB | Cam Newton | BP | 2/2016 | 353 | 37 | 0 | 4 | 0 | 0 | 0 | 28 | |
| QB | Matt Ryan | FM | 9/2016 | 344 | 0 | 0 | 4 | 0 | 0 | 0 | 28 | |
| QB | Tom Brady | BP | 8/2016 | 315 | 15 | 0 | 4 | 0 | 0 | 0 | 28 | |
| QB | Marcus Mariota | MHB | 9/2016 | 313 | 14 | 0 | 4 | 0 | 0 | 0 | 28 | |
| QB | Aaron Rodgers | SD | 8/2016 | 246 | 60 | 0 | 4 | 1 | 0 | 0 | 28 | |
| 13. | QB | Matt Ryan | FM | 2/2016 | 396 | 0 | 0 | 3 | 1 | 0 | 0 | 24 |
| QB | Marcus Mariota | MHB | 10/2016 | 295 | 8 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Tom Brady | BP | 11/2016 | 280 | 12 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Andrew Luck | MT | 13/2016 | 278 | 26 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Eli Manning | BB | 9/2016 | 257 | -4 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Philip Rivers | AE | 2/2016 | 220 | 10 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Aaron Rodgers | SD | 3/2016 | 205 | 22 | 0 | 4 | 0 | 0 | 0 | 24 | |
| QB | Derek Carr | LFT | 4/2016 | 199 | -2 | 0 | 4 | 0 | 0 | 0 | 24 | |
| 21. | QB | Ben Roethlisberger | LMM | 10/2016 | 408 | 1 | 0 | 3 | 0 | 0 | 0 | 23 |
| QB | Tom Brady | BP | 5/2016 | 406 | 14 | 0 | 3 | 0 | 0 | 0 | 23 | |
| QB | Jameis Winston | LFT | 3/2016 | 405 | 13 | 0 | 3 | 0 | 0 | 0 | 23 | |
| QB | Eli Manning | BB | 6/2016 | 403 | 0 | 0 | 3 | 0 | 0 | 0 | 23 | |
| 25. | QB | Drew Brees | CC | 3/2016 | 376 | 9 | 0 | 3 | 0 | 0 | 0 | 22 |